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For other uses, see Necrosis (disambiguation).
Not to be confused with Narcosis.
Necrosis
Structural changes of cells undergoing necrosis and apoptosis

Necrosis (from the Greek νέκρωσις "death, the stage of dying, the act of killing" from νεκρός "dead") is a form of cell injury which results in the premature death of cells in living tissue by autolysis.

Necrosis is caused by factors external to the cell or tissue, such as infection, toxins, or trauma which result in the unregulated digestion of cell components.

In contrast, apoptosis is a naturally occurring programmed and targeted cause of cellular death.

While apoptosis often provides beneficial effects to the organism, necrosis is almost always detrimental and can be fatal.

Cellular death due to necrosis does not follow the apoptotic signal transduction pathway, but rather various receptors are activated, and result in the loss of cell membrane integrity and an uncontrolled release of products of cell death into the extracellular space.

This initiates in the surrounding tissue an inflammatory response which prevents nearby phagocytes from locating and eliminating the dead cells by phagocytosis. For this reason, it is often necessary to remove necrotic tissue surgically, a procedure known as debridement. Untreated necrosis results in a build-up of decomposing dead tissue and cell debris at or near the site of the cell death. A classic example is gangrene.

Classification

Structural signs that indicate irreversible cell injury and the progression of necrosis include dense clumping and progressive disruption of genetic material, and disruption to membranes of cells and organelles.

Morphological patterns

There are six distinctive morphological patterns of necrosis:

  1. Coagulative necrosis is characterized by the formation of a gelatinous (gel-like) substance in dead tissues in which the architecture of the tissue is maintained, and can be observed by light microscopy. Coagulation occurs as a result of protein denaturation, causing albumin to transform into a firm and opaque state. This pattern of necrosis is typically seen in hypoxic (low-oxygen) environments, such as infarction. Coagulative necrosis occurs primarily in tissues such as the kidney, heart and adrenal glands. Severe ischemia most commonly causes necrosis of this form.
  2. Liquefactive necrosis (or colliquative necrosis), in contrast to coagulative necrosis, is characterized by the digestion of dead cells to form a viscous liquid mass. This is typical of bacterial, or sometimes fungal, infections because of their ability to stimulate an inflammatory response. The necrotic liquid mass is frequently creamy yellow due to the presence of dead leukocytes and is commonly known as pus. Hypoxic infarcts in the brain presents as this type of necrosis, because the brain contains little connective tissue but high amounts of digestive enzymes and lipids, and cells therefore can be readily digested by their own enzymes.
  3. Gangrenous necrosis can be considered a type of coagulative necrosis that resembles mummified tissue. It is characteristic of ischemia of lower limb and the gastrointestinal tracts. If superimposed infection of dead tissues occurs, then liquefactive necrosis ensues (wet gangrene)
  4. Caseous necrosis can be considered a combination of coagulative and liquefactive necrosis, typically caused by mycobacteria (e.g. tuberculosis), fungi and some foreign substances. The necrotic tissue appears as white and friable, like clumped cheese. Dead cells disintegrate but are not completely digested, leaving granular particles. Microscopic examination shows amorphous granular debris enclosed within a distinctive inflammatory border. Granuloma has this characteristic.
  5. Fat necrosis is specialized necrosis of fat tissue, resulting from the action of activated lipases on fatty tissues such as the pancreas. In the pancreas it leads to acute pancreatitis, a condition where the pancreatic enzymes leak out into the peritoneal cavity, and liquefy the membrane by splitting the triglyceride esters into fatty acids through fat saponification. Calcium, magnesium or sodium may bind to these lesions to produce a chalky-white substance. The calcium deposits are microscopically distinctive and may be large enough to be visible on radiographic examinations. To the naked eye, calcium deposits appear as gritty white flecks.
  6. Fibrinoid necrosis is a special form of necrosis usually caused by immune-mediated vascular damage. It is marked by complexes of antigen and antibodies, sometimes referred to as “immune complexes” deposited within arterial walls together with fibrin.

Other clinical classifications of necrosis

  1. There are also very specific forms of necrosis such as gangrene (term used in clinical practices for limbs which have suffered severe hypoxia), gummatous necrosis (due to spirochaetal infections) and hemorrhagic necrosis (due to the blockage of venous drainage of an organ or tissue).
  2. Some spider bites may lead to necrosis. In the United States, only spider bites from the brown recluse spider (genus Loxosceles) reliably progress to necrosis. In other countries, spiders of the same genus, such as the Chilean recluse in South America, are also known to cause necrosis. Claims that yellow sac spiders and hobo spiders possess necrotic venom have not been substantiated.
  3. In blind mole rats (genus Spalax), the process of necrosis replaces the role of the systematic apoptosis normally used in many organisms. Low oxygen conditions, such as those common in blind mole rats’ burrows, usually cause cells to undergo apoptosis. In adaptation to higher tendency of cell death, blind mole rats evolved a mutation in the tumor suppressor protein p53 (which is also used in humans) to prevent cells from undergoing apoptosis. Human cancer patients have similar mutations, and blind mole rats were thought to be more susceptible to cancer because their cells cannot undergo apoptosis. However, after a specific amount of time (within 3 days according to a study conducted at the University of Rochester), the cells in blind mole rats release interferon-beta (which the immune system normally uses to counter viruses) in response to over-proliferation of cells caused by the suppression of apoptosis. In this case, the interferon-beta triggers cells to undergo necrosis, and this mechanism also kills cancer cells in blind mole rats. Because of tumor suppression mechanisms such as this, blind mole rats and other spalacids are resistant to cancer.

Causes

Necrosis
Necrotic leg wound of cartoonist Jeffrey Rowland, caused by a brown recluse spider bite

Necrosis may occur due to external or internal factors.

External factors may involve mechanical trauma (physical damage to the body which causes cellular breakdown), damage to blood vessels (which may disrupt blood supply to associated tissue), and ischemia. Thermal effects (extremely high or low temperature) can result in necrosis due to the disruption of cells.

In frostbite, crystals form, increasing the pressure of remaining tissue and fluid causing the cells to burst. Under extreme conditions tissues and cells die through an unregulated process of destruction of membranes and cytosol.

Internal factors causing necrosis include: trophoneurotic disorders; injury and paralysis of nerve cells. Pancreatic enzymes (lipases) are the major cause of fat necrosis.

Necrosis can be activated by components of the immune system, such as the complement system; bacterial toxins; activated natural killer cells; and peritoneal macrophages. Pathogen-induced necrosis programs in cells with immunological barriers (intestinal mucosa) may alleviate invasion of pathogens through surfaces affected by inflammation. Toxins and pathogens may cause necrosis; toxins such as snake venoms may inhibit enzymes and cause cell death. Necrotic wounds have also resulted from the stings of Vespa mandarinia.

Pathological conditions are characterized by inadequate secretion of cytokines. Nitric oxide (NO) and reactive oxygen species (ROS) are also accompanied by intense necrotic death of cells. A classic example of a necrotic condition is ischemia which leads to a drastic depletion of oxygen, glucose, and other trophic factors and induces massive necrotic death of endothelial cells and non-proliferating cells of surrounding tissues (neurons, cardiomyocytes, renal cells, etc.). Recent cytological data indicates that necrotic death occurs not only during pathological events but it is also a component of some physiological process.

Activation-induced death of primary T-lymphocytes and other important constituents of the immune response are caspase-independent and necrotic by morphology; hence, current researchers have demonstrated that the occurrence of necrotic cell death can not only occur during pathological processes but also during normal processes such as tissue renewal, embryogenesis, and immune response.

Pathogenesis

Necrosis
Severe tissue necrosis following B. asper envenomation - the victim was an 11-year-old boy, bitten two weeks earlier in Ecuador, but treated only with antibiotics.

Until recently, necrosis was thought to be an unregulated process. There are two broad pathways in which necrosis may occur in an organism.

The first of these two pathways initially involves oncosis, where swelling of the cells occur. The cell then proceeds to blebbing, and this is followed by pyknosis, in which nuclear shrinkage transpires. In the final step of this pathway the nucleus is dissolved into the cytoplasm, which is referred to as karyolysis.

The second pathway is a secondary form of necrosis that is shown to occur after apoptosis and budding. Cellular changes of necrosis occur in this secondary form of apoptosis, where the nucleus breaks into fragments, which is known as karyorrhexis.

Cellular changes

The nucleus changes in necrosis, and characteristics of this change are determined by manner in which its DNA breaks down:

  • Karyolysis: the chromatin of the nucleus fades due to the loss of the DNA by degradation.
  • Pyknosis: the nucleus shrinks and the chromatin condenses.
  • Karyorrhexis: the shrunken nucleus fragments to complete dispersal.

Plasma alterations are also seen in necrosis. Plasma membranes appear discontinuous when viewed with an electron microscope. This discontinuous membrane is caused by cell blebbing and the loss of microvilli.

Treatment

There are many causes of necrosis, and as such treatment is based upon how the necrosis came about. Treatment of necrosis typically involves two distinct processes: Usually, the underlying cause of the necrosis must be treated before the dead tissue itself can be dealt with.

  • Debridement, referring to the removal of dead tissue by surgical or non-surgical means, is the standard therapy for necrosis. Depending on the severity of the necrosis, this may range from removal of small patches of skin, to complete amputation of affected limbs or organs. Chemical removal of necrotic tissue is another option in which enzymatic debriding agents, categorised as proteolytic, fibrinolytic or collagenases, are used to target the various components of dead tissue. In select cases, special maggot therapy using Lucilia sericata larvae has been employed to remove necrotic tissue and infection.
  • In the case of ischemia, which includes myocardial infarction, the restriction of blood supply to tissues causes hypoxia and the creation of reactive oxygen species (ROS) that react with, and damage proteins and membranes. Antioxidant treatments can be applied to scavenge the ROS.
  • Wounds caused by physical agents, including physical trauma and chemical burns, can be treated with antibiotics and anti-inflammatory drugs to prevent bacterial infection and inflammation. Keeping the wound clean from infection also prevents necrosis.
  • Chemical and toxic agents (e.g. pharmaceutical drugs, acids, bases) react with the skin leading to skin loss and eventually necrosis. Treatment involves identification and discontinuation of the harmful agent, followed by treatment of the wound, including prevention of infection and possibly the use of immunosuppressive therapies such as anti-inflammatory drugs or immunosuppressants. In the example of a snake bite, the use of anti-venom halts the spread of toxins whilst receiving antibiotics to impede infection.

Even after the initial cause of the necrosis has been halted, the necrotic tissue will remain in the body. The body's immune response to apoptosis, which involves the automatic breaking down and recycling of cellular material, is not triggered by necrotic cell death due to the apoptotic pathway being disabled.

In plants

If calcium is deficient, pectin cannot be synthesized, and therefore the cell walls cannot be bonded and thus an impediment of the meristems. This will lead to necrosis of stem and root tips and leaf edges. For example, necrosis of tissue can be found in the Arabidopsis thaliana due to plant pathogens.

See also

  • Avascular necrosis
  • Frostbite
  • Gangrene
  • Necrotizing fasciitis
  • Osteonecrosis of the jaw
  • Toxic epidermal necrolysis

References

  1. Proskuryakov SY, Konoplyannikov AG, Gabai VL (2003). "Necrosis: a specific form of programmed cell death?". Exp. Cell Res. 283 (1): 1–16. doi:10.1016/S0014-4827(02)00027-7. PMID 12565815.
  2. Kasper DL, Zaleznik DF (2001). "Gas gangrene, antibiotic associated colitis, and other Clostridial infections". In Stone RM. Harrison's principles of internal medicine self-assessment and board review (15th ed.). New York: McGraw-Hill, Medical Pub. Division. pp. 922–927. ISBN 0071386785.
  3. Craft J, Gordon C, Tiziani A, Huether SE, McCance KL, Brashers VL (2010). Understanding pathophysiology (1st ed.). Chatswood, N.S.W.: Elsevier Australia. ISBN 0729539512.
  4. Kumar V, Abbas AK, Aster JC, Fausto N (2010). Robbins and Cotran pathologic basis of disease (8th ed.). Philadelphia, PA: Saunders/Elsevier. pp. 12–41. ISBN 1416031219.
  5. McConnell TH (2007). The nature of disease: pathology for the health professions. Baltimore, Mar.: Lippincott Williams & Wilkins. ISBN 0781753171.
  6. Sattar (2015). Fundamentals of Pathology (2015th ed.). Chicago, IL: Pathoma LLC. p. 5. ISBN 978-0-9832246-2-4.
  7. Stevens A, Lowe JS, Young B, Deakin PJ (2002). Wheater's basic histopathology: a colour atlas and text (4th ed.). Edinburgh: Churchill Livingstone. ISBN 0443070016.
  8. Saey, Tina Hesman (5 November 2012). "Cancer cells self-destruct in blind mole rats". Science News. Society for Science and the Public. Retrieved 27 November 2012.
  9. Gorbunova V, Hine C, Tian X, Ablaeva J, Gudkov AV, Nevo E, Seluanov A (2012). "Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism". Proc. Natl. Acad. Sci. U.S.A. 109 (47): 19392–6. Bibcode:2012PNAS..10919392G. doi:10.1073/pnas.1217211109. PMC 3511137free to read. PMID 23129611.
  10. Raffray M, Cohen GM; Cohen (1997). "Apoptosis and necrosis in toxicology: a continuum or distinct modes of cell death?". Pharmacol. Ther. 75 (3): 153–77. doi:10.1016/s0163-7258(97)00037-5. PMID 9504137.
  11. Nazarian RM, Van Cott EM, Zembowicz A, Duncan LM (2009). "Warfarin-induced skin necrosis". J. Am. Acad. Dermatol. 61 (2): 325–32. doi:10.1016/j.jaad.2008.12.039. PMID 19615543.
  12. Yanagawa, Youichi (10 October 1980). "Cutaneous hemorrhage or necrosis findings after Vespa mandarinia (wasp) stings may predict the occurrence of multiple organ injury: A case report and review of literature". Clinical Toxicology (Informa Healthcare USA).
  13. Leg necrosis
  14. Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH, Blagosklonny MV, El-Deiry WS, Golstein P, Green DR, Hengartner M, Knight RA, Kumar S, Lipton SA, Malorni W, Nuñez G, Peter ME, Tschopp J, Yuan J, Piacentini M, Zhivotovsky B, Melino G, Nomenclature Committee on Cell Death 2009 (January 2009). "Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009" (PDF). Cell Death Differ. 16 (1): 3–11. doi:10.1038/cdd.2008.150. PMC 2744427free to read. PMID 18846107.
  15. Singhal A, Reis ED, Kerstein MD (2001). "Options for nonsurgical debridement of necrotic wounds". Adv Skin Wound Care. 14 (2): 96–100; quiz 102–3. PMID 11899913.
  16. Horobin AJ, Shakesheff KM, Pritchard DI (2005). "Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon the migration of human dermal fibroblasts over a fibronectin-coated surface". Wound Repair Regen. 13 (4): 422–33. doi:10.1111/j.1067-1927.2005.130410.x. PMID 16008732.
  17. Eum HA, Cha YN, Lee SM (2007). "Necrosis and apoptosis: sequence of liver damage following reperfusion after 60 min ischemia in rats". Biochem. Biophys. Res. Commun. 358 (2): 500–5. doi:10.1016/j.bbrc.2007.04.153. PMID 17490613.
  18. Cooper KL (2012). "Drug reaction, skin care, skin loss". Crit Care Nurse. 32 (4): 52–9. doi:10.4037/ccn2012340. PMID 22855079.
  19. Chotenimitkhun R, Rojnuckarin P; Rojnuckarin (2008). "Systemic antivenom and skin necrosis after green pit viper bites". Clin Toxicol (Phila). 46 (2): 122–5. doi:10.1080/15563650701266826. PMID 18259959.
  20. Edinger AL, Thompson CB; Thompson (2004). "Death by design: apoptosis, necrosis and autophagy". Curr. Opin. Cell Biol. 16 (6): 663–9. doi:10.1016/j.ceb.2004.09.011. PMID 15530778.
  21. Capon B (2010). Botany for gardeners (3rd ed.). Portland, Or.: Timber Press. ISBN 978-1-60469-095-8.

External links

  • Life In The Fast Lane: toxicology Conundrum #018
  • Undersea and Hyperbaric Medical Society. "Necrotizing Soft Tissue Infections". Retrieved 25 July 2008.
  • Secondary necrosis of a neutrophil

Necrosis

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Of course, the goods related with "Necrosis" in Kentucky can be delivered to Louisville, Lexington, Bowling Green, Owensboro, Covington, Hopkinsville, Richmond, Florence, Georgetown, Henderson, Elizabethtown, Nicholasville, Jeffersontown, Frankfort, Paducah, Independence, Radcliff, Ashland, Madisonville, Winchester, Erlanger, Murray, St. Matthews, Fort Thomas, Danville, Newport, Shively, Shelbyville, Glasgow, Berea, Bardstown, Shepherdsville, Somerset, Lyndon, Lawrenceburg, Middlesboro, Mayfield and smaller towns.

It goes without saying that the goods named "Necrosis" in Louisiana can be bought in New Orleans, Baton Rouge, Shreveport, Metairie, Lafayette, Lake Charles, Kenner, Bossier City, Monroe, Alexandria, Houma, Marrero, New Iberia, Laplace, Slidell, Prairieville, Central, Terrytown, Ruston, Sulphur, Harvey, Hammond, Bayou Cane, Shenandoah, Natchitoches, Gretna, Chalmette, Opelousas, Estelle, Zachary, and so on.

No doubt, the goods related with "Necrosis" in Maine can be sent to Portland, Lewiston, Bangor, South Portland, Auburn, Biddeford, Sanford, Saco, Augusta, Westbrook, Waterville, Presque Isle, Brewer, Bath, Caribou, Ellsworth, Old Town, Rockland, Belfast, Gardiner, Calais, Hallowell, Eastport...

Normally, any things related with "Necrosis" in Maryland can be received in such cities as Baltimore, Frederick, Rockville, Gaithersburg, Bowie, Hagerstown, Annapolis, College Park, Salisbury, Laurel, Greenbelt, Cumberland, Westminster, Hyattsville, Takoma Park, Easton, Elkton, Aberdeen, Havre de Grace, Cambridge, New Carrollton, Bel Air...

No need to say, the goods related with "Necrosis" in Massachusetts can be shipped to Boston, Worcester, Springfield, Lowell, Cambridge, New Bedford, Brockton, Quincy, Lynn, Fall River, Newton, Lawrence, Somerville, Framingham, Haverhill, Waltham, Malden, Brookline, Plymouth, Medford, Taunton, Chicopee, Weymouth, Revere, Peabody, Methuen, Barnstable, Pittsfield, Attleboro, Arlington, Everett, Salem, Westfield, Leominster, Fitchburg, Billerica, Holyoke, Beverly, Marlborough, Woburn, Amherst, Braintree, Shrewsbury, Chelsea, Dartmouth, Chelmsford, Andover, Natick, Randolph, Watertown, and other cities.

Today the products by request "Necrosis" in Michigan can be bought in Detroit, Grand Rapids, Warren, Sterling Heights, Lansing, Ann Arbor, Flint, Dearborn, Livonia, Clinton, Canton, Westland, Troy, Farmington Hills, Macomb Township, Kalamazoo, Shelby, Wyoming, Southfield, Waterford, Rochester Hills, West Bloomfield, Taylor, Saint Clair Shores, Pontiac, Dearborn Heights, Royal Oak, Novi, Ypsilanti, Battle Creek, Saginaw, Kentwood, East Lansing, Redford, Roseville, Georgetown, Portage, Chesterfield Township, Midland, Bloomfield Charter Township, Oakland County, Saginaw, Commerce, Meridian, Muskegon, Lincoln Park, Grand Blanc, Holland, Orion, Bay City, Independence Charter Township, and so on.

As you know, the products related to the term "Necrosis" in Minnesota can be purchased if you live in Minneapolis, Saint Paul, Rochester, Bloomington, Duluth, Brooklyn Park, Plymouth, Maple Grove, Woodbury, St. Cloud, Eagan, Eden Prairie, Coon Rapids, Blaine, Burnsville, Lakeville, Minnetonka, Apple Valley, Edina, St. Louis Park, Moorhead, Mankato, Maplewood, Shakopee, Richfield, Cottage Grove, Roseville, Inver Grove Heights, Andover, Brooklyn Center, Savage, Oakdale, Fridley, Winona, Shoreview, Ramsey, Owatonna, Chanhassen, Prior Lake, White Bear Lake, Chaska, Austin, Elk River, Champlin, Faribault, Rosemount, Crystal, Farmington, Hastings, New Brighton and smaller towns.

And the found goods by query "Necrosis" in Mississippi can be shipped to such cities as Jackson, Gulfport, Southaven, Hattiesburg, Biloxi, Meridian, Tupelo, Greenville, Olive Branch, Horn Lake, Clinton, Pearl, Ridgeland, Starkville, Columbus, Vicksburg, Pascagoula, Clarksdale, Oxford, Laurel, Gautier, Ocean Springs, Madison, Brandon, Greenwood, Cleveland, Natchez, Long Beach, Corinth, Hernando, Moss Point, McComb, Canton, Carriere, Grenada, Brookhaven, Indianola, Yazoo City, West Point, Picayune, Petal, and other cities.

As always, any products related with "Necrosis" in Missouri can be received in such cities as Kansas City, St. Louis, Springfield, Independence, Columbia, Lee’s Summit, O’Fallon, St. Joseph, St. Charles, Blue Springs, St. Peters, Florissant, Joplin, Chesterfield, Jefferson City, Cape Girardeau, Oakville, Wildwood, University City, Ballwin, Raytown, Liberty, Wentzville, Mehlville, Kirkwood, Maryland Heights, Hazelwood, Gladstone, Grandview, Belton, Webster Groves, Sedalia, Ferguson, Arnold, Affton, and other cities.

No need to say, the found goods by query "Necrosis" in Montana can be received in Billings, Missoula, Great Falls, Bozeman, Butte, Helena, Kalispell, Havre, Anaconda, Miles City, Belgrade, Livingston, Laurel, Whitefish, Lewistown, Sidney and smaller towns.

As usual, any products related with "Necrosis" in Nebraska can be delivered to the following cities: Omaha, Lincoln, Bellevue, Grand Island, Kearney, Fremont, Hastings, Norfolk, North Platte, Papillion, Columbus, La Vista, Scottsbluff, South Sioux City, Beatrice, Lexington, and so on.

As always, the products by request "Necrosis" in Nevada can be delivered to the following cities: Las Vegas, Henderson, Reno, North Las Vegas, Sparks, Carson City, Fernley, Elko, Mesquite, Boulder City, Fallon, Winnemucca, West Wendover, Ely, Yerington, Carlin, Lovelock, Wells, Caliente, and other cities and towns.

Today the goods named "Necrosis" in New Hampshire can be delivered to Manchester, Nashua, Concord, Derry, Dover, Rochester, Salem, Merrimack, Hudson, Londonderry, Keene, Bedford, Portsmouth, Goffstown, Laconia, Hampton, Milford, Durham, Exeter, Windham, Hooksett, Claremont, Lebanon, Pelham, Somersworth, Hanover, Amherst, Raymond, Conway, Berlin.

Naturally, the goods named "Necrosis" in New Jersey can be received in Newark, Jersey City, Paterson, Elizabeth, Edison, Woodbridge, Lakewood, Toms River, Hamilton, Trenton, Clifton, Camden, Brick, Cherry Hill, Passaic, Middletown, Union City, Old Bridge, Gloucester Township, East Orange, Bayonne, Franklin, North Bergen, Vineland, Union, Piscataway, New Brunswick, Jackson, Wayne, Irvington, Parsippany-Troy Hills, Howell, Perth Amboy, Hoboken, Plainfield, West New York, Washington Township, East Brunswick, Bloomfield, West Orange, Evesham, Bridgewater, South Brunswick, Egg Harbor, Manchester, Hackensack, Sayreville, Mount Laurel, Berkeley, North Brunswick...

It goes without saying that the goods by request "Necrosis" in New Mexico can be bought in Albuquerque, Las Cruces, Rio Rancho, Santa Fe, Roswell, Farmington, South Valley, Clovis, Hobbs, Alamogordo, Carlsbad, Gallup, Deming, Los Lunas, Chaparral, Sunland Park, Las Vegas, Portales, Los Alamos, North Valley, Artesia, Lovington, Silver City, Española.

No doubt, the goods named "Necrosis" in New York can be received in such cities as New York, Buffalo, Rochester, Yonkers, Syracuse, Albany, New Rochelle, Mount Vernon, Schenectady, Utica, White Plains, Troy, Niagara Falls, Binghamton, Rome, Long Beach, Poughkeepsie, North Tonawanda, Jamestown, Ithaca, Elmira, Newburgh, Middletown, Auburn, Watertown, Glen Cove, Saratoga Springs, Kingston, Peekskill, Lockport, Plattsburgh, Cortland, Amsterdam, Oswego, Lackawanna, Cohoes, Rye, Gloversville, Beacon, Batavia, Tonawanda, Glens Falls, Olean, Oneonta, Geneva, Dunkirk, Fulton, Oneida, Corning, Ogdensburg, Canandaigua, Watervliet, etc.

Naturally, the goods named "Necrosis" in North Carolina can be sent to Charlotte, Raleigh, Greensboro, Durham, Winston-Salem, Fayetteville, Cary, Wilmington, High Point, Greenville, Asheville, Concord, Gastonia, Jacksonville, Chapel Hill, Rocky Mount, Huntersville, Burlington, Wilson, Kannapolis, Apex, Hickory, Wake Forest, Indian Trail, Mooresville, Goldsboro, Monroe, Salisbury, Holly Springs, Matthews, New Bern, Sanford, Cornelius, Garner, Thomasville, Statesville, Asheboro, Mint Hill, Fuquay-Varina, Morrisville, Kernersville, Lumberton, Kinston, Carrboro, Havelock, Shelby, Clemmons, Lexington, Clayton, Boone...

Usually, any products related with "Necrosis" in North Dakota can be delivered to Fargo, Bismarck, Grand Forks, Minot, West Fargo, Williston, Dickinson, Mandan, Jamestown, Wahpeton, Devils Lake, Watford City, Valley City, Grafton, Lincoln, Beulah, Rugby, Stanley, Horace, Casselton, New Town, Hazen, Bottineau, Lisbon, Carrington, and other cities.

Naturally, the products by request "Necrosis" in Ohio can be received in Columbus, Cleveland, Cincinnati, Toledo, Akron, Dayton, Parma, Canton, Youngstown, Lorain, Hamilton, Springfield, Kettering, Elyria, Lakewood, Cuyahoga Falls, Euclid, Middletown, Mansfield, Newark, Mentor, Cleveland Heights, Beavercreek, Strongsville, Fairfield, Dublin, Warren, Findlay, Lancaster, Lima, Huber Heights, Marion, Westerville, Reynoldsburg, Grove City, Stow, Delaware, Brunswick, Upper Arlington, Gahanna, Westlake, North Olmsted, Fairborn, Massillon, Mason, North Royalton, Bowling Green, North Ridgeville, Kent, Garfield Heights, etc.

Usually, the products related to the term "Necrosis" in Oklahoma can be shipped to such cities as Oklahoma City, Tulsa, Norman, Broken Arrow, Lawton, Edmond, Moore, Midwest City, Enid, Stillwater, Muskogee, Bartlesville, Owasso, Shawnee, Yukon, Ardmore, Ponca City, Bixby, Duncan, Del City, Jenks, Sapulpa, Mustang, Sand Springs, Bethany, Altus, Claremore, El Reno, McAlester, Ada, Durant, Tahlequah, Chickasha, Miami, Glenpool, Elk City, Woodward, Okmulgee, Choctaw, Weatherford, Guymon, Guthrie, Warr Acres, and other cities.

And of course, the found goods by query "Necrosis" in Oregon can be shipped to Portland, Salem, Eugene, Gresham, Hillsboro, Beaverton, Bend, Medford, Springfield, Corvallis, Albany, Tigard, Lake Oswego, Keizer, Grants Pass, Oregon City, McMinnville, Redmond, Tualatin, West Linn, Woodburn, Forest Grove, Newberg, Wilsonville, Roseburg, Klamath Falls, Ashland, Milwaukie, Sherwood, Happy Valley, Central Point, Canby, Hermiston, Pendleton, Troutdale, Lebanon, Coos Bay, The Dalles, Dallas, St. Helens, La Grande, Cornelius, Gladstone, Ontario, Sandy, Newport, Monmouth, etc.

As always, the goods related with "Necrosis" in Pennsylvania can be shipped to Philadelphia, Pittsburgh, Allentown, Erie, Reading, Scranton, Bethlehem, Lancaster, Harrisburg, Altoona, York, Wilkes-Barre, Chester, Williamsport, Easton, Lebanon, Hazleton, New Castle, Johnstown, McKeesport, Hermitage, Greensburg, Pottsville, Sharon, Butler, Washington, Meadville, New Kensington, Coatesville, St. Marys, Lower Burrell, Oil City, Nanticoke, Uniontown, and other cities.

And the goods named "Necrosis" in Rhode Island can be delivered to the following cities: Providence, Warwick, Cranston, Pawtucket, East Providence, Woonsocket, Coventry, Cumberland, North Providence, South Kingstown, West Warwick, Johnston, North Kingstown, Newport, Bristol, Westerly, Smithfield, Lincoln, Central Falls, Portsmouth, Barrington, Middletown, Burrillville, Narragansett, Tiverton, East Greenwich, North Smithfield, Warren, Scituate, and other cities.

And the goods related with "Necrosis" in South Carolina can be sent to Columbia, Charleston, North Charleston, Mount Pleasant, Rock Hill, Greenville, Summerville, Sumter, Hilton Head Island, Spartanburg, Florence, Goose Creek, Aiken, Myrtle Beach, Anderson, Greer, Mauldin, Greenwood, North Augusta, Easley, Simpsonville, Hanahan, Lexington, Conway, West Columbia, North Myrtle Beach, Clemson, Orangeburg, Cayce, Bluffton, Beaufort, Gaffney, Irmo, Fort Mill, Port Royal, Forest Acres, Newberry and smaller towns.

Usually, any products related with "Necrosis" in South Dakota can be shipped to such cities as Sioux Falls, Rapid City, Aberdeen, Brookings, Watertown, Mitchell, Yankton, Pierre, Huron, Spearfish, Vermillion...

Normally, the products related to the term "Necrosis" in Tennessee can be shipped to such cities as Memphis, Nashville, Knoxville, Chattanooga, Clarksville, Murfreesboro, Franklin, Jackson, Johnson City, Bartlett, Hendersonville, Kingsport, Collierville, Smyrna, Cleveland, Brentwood, Germantown, Columbia, Spring Hill, La Vergne, Gallatin, Cookeville, Mount Juliet, Lebanon, Morristown, Oak Ridge, Maryville, Bristol, Farragut, Shelbyville, East Ridge, Tullahoma, etc.

No doubt, any products related with "Necrosis" in Texas can be purchased if you live in Houston, San Antonio, Dallas, Austin, Fort Worth, El Paso, Arlington, Corpus Christi, Plano, Laredo, Lubbock, Garland, Irving, Amarillo, Grand Prairie, Brownsville, McKinney, Frisco, Pasadena, Mesquite, Killeen, McAllen, Carrollton, Midland, Waco, Denton, Abilene, Odessa, Beaumont, Round Rock, The Woodlands, Richardson, Pearland, College Station, Wichita Falls, Lewisville, Tyler, San Angelo, League City, Allen, Sugar Land, Edinburg, Mission, Longview, Bryan, Pharr, Baytown, Missouri City, Temple, Flower Mound, New Braunfels, North Richland Hills, Conroe, Victoria, Cedar Park, Harlingen, Atascocita, Mansfield, Georgetown, San Marcos, Rowlett, Pflugerville, Port Arthur, Spring, Euless, DeSoto, Grapevine, Galveston, and other cities and towns.

No need to say, the goods named "Necrosis" in Utah can be shipped to such cities as Salt Lake City, West Valley City, Provo, West Jordan, Orem, Sandy, Ogden, St. George, Layton, Taylorsville, South Jordan, Logan, Lehi, Murray, Bountiful, Draper, Riverton, Roy, Spanish Fork, Pleasant Grove, Cottonwood Heights, Tooele, Springville, Cedar City, Midvale. You can also buy these goods in Kaysville, Holladay, American Fork, Clearfield, Syracuse, South Salt Lake, Herriman, Eagle Mountain, Clinton, Washington, Payson, Farmington, Brigham City, Saratoga Springs, North Ogden, South Ogden, North Salt Lake, Highland, Centerville, Hurricane, Heber City, West Haven, Lindon.

And of course, any things related with "Necrosis" in Vermont can be sent to Burlington, South Burlington, Rutland, Barre, Montpelier, Winooski, St. Albans, Newport, Vergennes, and so on.

It goes without saying that the products by request "Necrosis" in Virginia can be shipped to such cities as Virginia Beach, Norfolk, Chesapeake, Richmond, Newport News, Alexandria, Hampton, Roanoke, Portsmouth, Suffolk, Lynchburg, Harrisonburg, Charlottesville, Danville, Manassas, Petersburg, Fredericksburg, Winchester, Salem, Staunton, Fairfax, Hopewell, Waynesboro, Colonial Heights, Radford, Bristol, Manassas Park, Williamsburg, Falls Church, Martinsville, Poquoson and smaller towns.

Normally, the goods by request "Necrosis" in Washington can be received in such cities as Seattle, Spokane, Tacoma, Vancouver, Bellevue, Kent, Everett, Renton, Federal Way, Yakima, Spokane Valley, Kirkland, Bellingham, Kennewick, Auburn, Pasco, Marysville, Lakewood, Redmond, Shoreline, Richland, Sammamish, Burien, Olympia, Lacey. As well as in Edmonds, Puyallup, Bremerton, Lynnwood, Bothell, Longview, Issaquah, Wenatchee, Mount Vernon, University Place, Walla Walla, Pullman, Des Moines, Lake Stevens, SeaTac, Maple Valley, Mercer Island, Bainbridge Island, Oak Harbor, Kenmore, Moses Lake, Camas, Mukilteo, Mountlake Terrace, Tukwila...

Naturally, the goods by request "Necrosis" in West Virginia can be shipped to Charleston, Huntington, Morgantown, Parkersburg, Wheeling, Weirton, Fairmont, Martinsburg, Beckley, Clarksburg, South Charleston, St. Albans, Vienna, Bluefield and smaller towns.

And of course, the products related to the term "Necrosis" in Wisconsin can be delivered to Milwaukee, Madison, Green Bay, Kenosha, Racine, Appleton, Waukesha, Oshkosh, Eau Claire, Janesville, West Allis, La Crosse, Sheboygan, Wauwatosa, Fond du Lac, New Berlin, Wausau. Delivery is also carried out in Brookfield, Beloit, Greenfield, Franklin, Oak Creek, Manitowoc, West Bend, Sun Prairie, Superior, Stevens Point, Neenah, Fitchburg, Muskego, Watertown, De Pere, Mequon, South Milwaukee, Marshfield, etc.

And of course, the goods named "Necrosis" in Wyoming can be purchased if you live in Cheyenne, Casper, Laramie, Gillette, Rock Springs, Sheridan, Green River, Evanston, Riverton, Jackson, Cody, Rawlins, Lander, Torrington, Powell, Douglas, Worland and smaller towns.

Canada Delivery, Shipping to Canada

And today the goods named "Necrosis" in Canada can be received in such cities as Toronto, Montreal, Calgary, Ottawa, Edmonton, Mississauga, Winnipeg, Vancouver, Brampton, Hamilton, Quebec City, Surrey, Laval, Halifax, London, Markham, Vaughan, Gatineau, Longueuil, Burnaby, Saskatoon, Kitchener, Windsor, Regina, Richmond, Richmond Hill.

As well as in Oakville, Burlington, Greater Sudbury, Sherbrooke, Oshawa, Saguenay, Lévis, Barrie, Abbotsford, St. Catharines, Trois-Rivières, Cambridge, Coquitlam, Kingston, Whitby, Guelph, Kelowna, Saanich, Ajax, Thunder Bay, Terrebonne, St. John's, Langley, Chatham-Kent, Delta.

The shipping is also available in Waterloo, Cape Breton, Brantford, Strathcona County, Saint-Jean-sur-Richelieu, Red Deer, Pickering, Kamloops, Clarington, North Vancouver, Milton, Nanaimo, Lethbridge, Niagara Falls, Repentigny, Victoria, Newmarket, Brossard, Peterborough, Chilliwack, Maple Ridge, Sault Ste. Marie, Kawartha Lakes, Sarnia, Prince George.

It's also available for those who live in Drummondville, Saint John, Moncton, Saint-Jérôme, New Westminster, Wood Buffalo, Granby, Norfolk County, St. Albert, Medicine Hat, Caledon, Halton Hills, Port Coquitlam, Fredericton, Grande Prairie, North Bay, Blainville, Saint-Hyacinthe, Aurora, Welland, Shawinigan, Dollard-des-Ormeaux, Belleville, North Vancouver, etc.

Actually, the goods by request "Necrosis" can be shipped to any place in Canada, including Ontario, Quebec, British Columbia, Alberta, Manitoba, Saskatchewan, Nova Scotia, New Brunswick, Newfoundland and Labrador, and Prince Edward Island.

UK Delivery, Shipping to the United Kingdom

And today the goods by your query "Necrosis" in the United Kingdom can be delivered to the following cities: London, Birmingham, Leeds, Glasgow, Sheffield, Bradford, Edinburgh, Liverpool, Manchester, Bristol, Wakefield, Cardiff, Coventry, Nottingham, Leicester, Sunderland, Belfast, Newcastle upon Tyne, Brighton, Hull, Plymouth, Stoke-on-Trent.

You can also buy these goods in Wolverhampton, Derby, Swansea, Southampton, Salford, Aberdeen, Westminster, Portsmouth, York, Peterborough, Dundee, Lancaster, Oxford, Newport, Preston, St Albans, Norwich, Chester, Cambridge, Salisbury, Exeter, Gloucester. And other cities and towns, such as Lisburn, Chichester, Winchester, Londonderry, Carlisle, Worcester, Bath, Durham, Lincoln, Hereford, Armagh, Inverness, Stirling, Canterbury, Lichfield, Newry, Ripon, Bangor, Truro, Ely, Wells, St. Davids, and other cities.

Basically, any things related with "Necrosis" can be shipped to any place in the UK, including England, Scotland, Wales, and Northern Ireland.

Ireland Delivery, Shipping to Ireland

It goes without saying that the goods named "Necrosis" in Ireland can be received in Dublin, Cork, Limerick, Galway, Waterford, Drogheda, Dundalk, Swords, Bray, Navan, Ennis, Kilkenny, Tralee, Carlow, Newbridge, Naas, Athlone, Portlaoise, Mullingar, Wexford, Balbriggan, Letterkenny, Celbridge, Sligo. And also in Clonmel, Greystones, Malahide, Leixlip, Carrigaline, Tullamore, Killarney, Arklow, Maynooth, Cobh, Castlebar, Midleton, Mallow, Ashbourne, Ballina, Laytown-Bettystown-Mornington, Enniscorthy, Wicklow, Tramore, Cavan, and so on.

Generally, the products related to the term "Necrosis" can be shipped to any place in Ireland, including Leinster, Ulster, Munster, and Connacht.

Australia Delivery, Shipping to Australia

Normally, any things related with "Necrosis" in Australia can be bought in Sydney, Melbourne, Brisbane, Perth, Adelaide, Gold Coast, Tweed Heads, Newcastle, Maitland, Canberra, Queanbeyan, Sunshine Coast, Wollongong, Hobart, Geelong, Townsville, Cairns, Darwin, Toowoomba, Ballarat, Bendigo, Albury, Wodonga, Launceston, Mackay.

And also in Rockhampton, Bunbury, Bundaberg, Coffs Harbour, Wagga Wagga, Hervey Bay, Mildura, Wentworth, Shepparton, Mooroopna, Gladstone, Tannum Sands, Port Macquarie, Tamworth, Traralgon, Morwell, Orange, Geraldton, Bowral, Mittagong, Dubbo, Busselton, Bathurst, Nowra, Bomaderry, Warrnambool, Albany, Warragul, Drouin, Kalgoorlie, Boulder, Devonport.

In fact, any things related with "Necrosis" can be shipped to any place in Australia, including New South Wales, Victoria, Queensland, Western Australia, South Australia, Tasmania, Australian Capital Territory, and Northern Territory.

New Zealand Delivery, Shipping to New Zealand

And of course, any things related with "Necrosis" in New Zealand can be sent to Auckland, Wellington, Christchurch, Hamilton, Tauranga, Napier-Hastings, Dunedin, Lower Hutt, Palmerston North, Nelson, Rotorua, New Plymouth, Whangarei, Invercargill, Whanganui, Gisborne, Porirua, Invercargill, Nelson, Upper Hutt, Gisborne, Blenheim, Pukekohe, Timaru, Taupo, and other cities.

Basically, the goods by request "Necrosis" can be shipped to any place in New Zealand, including North Island, South Island, Waiheke Island, and smaller islands. Naturally,the goods by requestcan be shipped to such cities asAs well as in, etc.

In fact,

Delivery

Abkhazia: Gagra, Gudauta, New Athos, Ochamchire, Pitsunda, Sukhumi, Tsandryphsh, etc.

Afghanistan: Herat, Jalalabad, Kabul, Kandahar, Kunduz, Mazar-i-Sharif, Taloqan, etc.

Albania: Durrës, Himarë, Sarandë, Shkodër, Tirana, Vlorë, etc.

Algeria: Algiers, Oran, etc.

Andorra: Andorra la Vella, Arinsal, El Pas de la Casa, Encamp, Grandvalira, Ordino, Pal, Soldeu, Vallnord, etc.

Angola: Benguela, Luanda, etc.

Anguilla: The Valley, West End, etc.

Antigua And Barbuda: Saint John’s, etc.

Argentina: Buenos Aires, Colón, Córdoba, El Calafate, La Plata, Los Glaciares, Mar del Plata, Mendoza, Pinamar, Puerto Iguazú, Puerto Madryn, Rosario, Salta, San Carlos de Bariloche, San Martín de los Andes, San Miguel de Tucumán, San Rafael, Tandil, Tierra del Fuego, Ushuaia, Villa Carlos Paz, Villa Gesell, Villa La Angostura, Villa de Merlo, etc.

Armenia: Dilijan, Etchmiadzin, Goris, Gyumri, Jermuk, Sevan, Tsaghkadzor, Vagharshapat, Vanadzor, Yerevan, etc.

Aruba: Oranjestad, etc.

Australia: Adelaide, Brisbane, Byron Bay, Cairns, Canberra, Darwin, Gold Coast, Great Barrier Reef, Hobart, Melbourne, Perth, Sydney, Tasmania, etc.

Austria: Abtenau, Alpbach, Austrian Alps, Bad Gastein, Bad Hofgastein, Bad Kleinkirchheim, Dürnstein, Flachau, Fugen, Graz, Innsbruck, Ischgl, Kaprun, Kitzbühel, Klagenfurt, Kufstein, Lech, Leogang, Lienz, Linz, Maria Alm, Mayrhofen, Neustift im Stubaital, Obergurgl, Saalbach-Hinterglemm, Saalfelden, Salzburg, Schladming, Seefeld, Serfaus, St. Anton, St. Johann im Pongau, Sölden, Tux, Tyrol, Vienna, Villach, Wachau, Wagrain, Zell am See, etc.

Azerbaijan: Baku, Ganja, Lankaran, Quba, Qusar, Shahdag, Sheki, Stepanakert, etc.

Bahamas: Freeport, Nassau, etc.

Bahrain: Manama, etc.

Bangladesh: Chittagong, Cox's Bazar, Dhaka, Khulna, Narayanganj, Rajshahi, Sylhet, etc.

Barbados: Bridgetown, etc.

Belarus: Babruysk, Białowieża Forest, Brest Belarus, Gomel, Grodno, Lahoysk, Maladzyechna, Minsk, Mogilev, Nesvizh, Pinsk, Silichi, Vitebsk, etc.

Belgium: Antwerp, Ardennes, Blankenberge, Bouillon, Bruges, Brussels, Charleroi, De Haan, De Panne, Durbuy, Flanders, Ghent, Hasselt, Kortrijk, Leuven, Liège, Namur, Nieuwpoort, Ostend, Spa, Ypres, Zeebrugge, etc.

Belize: Belize City, Placencia, San Pedro, etc.

Benin: Cotonou, etc.

Bermuda: Hamilton, etc.

Bhutan: Paro, Thimphu, etc.

Bolivia: Cochabamba, El Alto, La Paz, Oruro, Quillacollo, Santa Cruz de la Sierra, Sucre, Uyuni, etc.

Bosnia and Herzegovina: Banja Luka, Jahorina, Medjugorje, Mostar, Neum, Sarajevo, etc.

Botswana: Gaborone, Maun, etc.

Brazil: Amazon River, Amazonia, Angra dos Reis, Arraial do Cabo, Atlantic Forest, Balneário Camboriú, Belo Horizonte, Bombinhas, Brasília, Búzios, Cabo Frio, Camaçari, Campos do Jordão, Copacabana, Costa do Sauípe, Curitiba, Fernando de Noronha, Florianópolis, Fortaleza, Foz do Iguaçu, Gramado, Guarujá, Iguazu Falls, Ilha Grande, Ilhabela, Ilhéus, Ipanema, Itacaré, Manaus, Morro de São Paulo, Natal, Niterói, Ouro Preto, Paraty, Petrópolis, Porto Alegre, Porto Seguro, Praia do Forte, Recife, Rio de Janeiro, Salvador, São Paulo, São Sebastião, Trancoso, Ubatuba, Vila do Abraão, etc.

British Virgin Islands: Tortola, etc.

Brunei: Bandar Seri Begawan, etc.

Bulgaria: Albena, Balchik, Bansko, Blagoevgrad, Borovets, Burgas, Chernomorets, Dobrinishte, Golden Sands, Kiten, Koprivshtitsa, Lozenets, Nesebar, Obzor, Pamporovo, Pirin, Pleven, Plovdiv, Pomorie, Primorsko, Ravda, Razlog, Rila, Ruse, Samokov, Sandanski, Shumen, Sofia, Sozopol, Stara Zagora, Sunny Beach, Sveti Vlas, Tsarevo, Varna, Veliko Tarnovo, etc.

Burkina Faso: Ouagadougou, etc.

Burundi: Bujumbura, etc.

Cambodia: Angkor, Battambang, Kampot, Kep, Phnom Penh, Siem Reap, Sihanoukville, etc.

Cameroon: Bafoussam, Bamenda, Douala, Garoua, Kribi, Limbe, Maroua, Yaoundé, etc.

Canada: Alberta, Banff, British Columbia, Burnaby, Calgary, Charlottetown, Edmonton, Fort McMurray, Halifax, Jasper, Kamloops, Kelowna, Kingston, London, Manitoba, Mississauga, Moncton, Mont-Tremblant, Montreal, Nanaimo, New Brunswick, Niagara Falls, Niagara on the Lake, Nova Scotia, Ontario, Ottawa, Prince Edward Island, Quebec, Richmond, Saskatchewan, Saskatoon, Surrey, Toronto, Vancouver, Victoria, Whistler, Whitehorse, Winnipeg, Yukon, etc.

Cape Verde: Boa Vista Cape Verde, Sal, etc.

Caribbean Netherlands:, etc.

Cayman Islands: George Town, West Bay, etc.

Chad: N'Djamena, etc.

Chile: Antofagasta, Arica, Atacama, Coquimbo, Easter Island, Hanga Roa, Iquique, La Serena, Patagonia, Pucón, Puerto Montt, Puerto Natales, Puerto Varas, Punta Arenas, San Pedro de Atacama, Santiago, Torres del Paine, Valdivia, Valparaíso, Villarrica, Viña del Mar, etc.

China: Anshun, Baishan, Baoding, Baoshan, Baotou, Beijing, Binzhou, Changchun, Changsha, Changzhi, Chengdu, Chongqing, Dali, Dalian, Datong, Dengfeng, Diqing, Dongguan, Emeishan, Foshan, Great Wall of China, Guangdong, Guangzhou, Guilin, Guiyang, Hainan, Hangzhou, Harbin, Honghe, Huashan, Huizhou, Jiangmen, Jiangxi, Jiaxing, Jilin, Jinan, Jincheng, Jingdezhen, Jinzhong, Jiujiang, Jiuzhaigou, Kunming, Langfang, Lanzhou, Laoshan, Leshan, Lhasa, Lianyungang, Lijiang, Linfen, Linyi, Luoyang, Lushan, Lüliang, Mianyang, Nanchang, Nanchong, Nanjing, Nantong, Ngawa, Ningbo, Qiandongnan, Qingdao, Qingyuan, Qinhuangdao, Qujing, Rizhao, Sanya, Shanghai, Shangri-La, Shantou, Shanxi, Shaoguan, Shaolin, Shaoxing, Shenyang, Shenzhen, Shigatse, Shijiazhuang, Sichuan, Suzhou, Tai'an, Taiyuan, Taizhou Jiangsu, Tangshan, Tianjin, Tibet, Weifang, Weihai, Wuhan, Wulingyuan, Wutai, Wuxi, Xi'an, Xiamen, Xinzhou, Xishuangbanna, Ya'an, Yanbian, Yangtze, Yangzhou, Yantai, Yellow River, Yibin, Yinchuan, Yiwu, Yuncheng, Yunnan, Zhangjiajie, Zhanjiang, Zhejiang, Zhengzhou, Zhongshan, Zhongwei, Zhoushan, Zhuhai, Zunyi, etc.

Colombia: Barranquilla, Bogotá, Bucaramanga, Cali, Cartagena, Medellín, Pereira, San Andrés, Santa Marta, Villa de Leyva, Villavicencio, etc.

Costa Rica: Alajuela, Jacó, La Fortuna, Manuel Antonio, Monteverde, Puerto Viejo de Talamanca, Puntarenas, Quepos, San José, Santa Teresa, Tamarindo, Tortuguero, etc.

Croatia: Baška Voda, Baška, Bibinje, Biograd na Moru, Bol, Brač, Brela, Cavtat, Cres, Dalmatia, Fažana, Hvar, Istria, Ičići, Korčula, Krk, Lopud, Lovran, Lošinj, Makarska, Mali Lošinj, Malinska, Medulin, Mlini, Nin, Novi Vinodolski, Novigrad, Omiš, Opatija, Orebić, Pag, Podstrana, Poreč, Pula, Rab, Rabac, Rijeka, Rovinj, Split, Stari Grad, Sukošan, Supetar, Trogir, Tučepi, Umag, Vrsar, Zadar, Zagreb, Čiovo, Šibenik, etc.

Cuba: Baracoa, Camagüey, Cayo Coco, Cayo Santa María, Cienfuegos, Havana, Pinar del Río, Santiago de Cuba, Trinidad, Varadero, Viñales, etc.

Curaçao: Willemstad, etc.

Cyprus: Ayia Napa, Coral Bay Cyprus, Famagusta, Kouklia, Kyrenia, Larnaca, Limassol, Nicosia, Paphos, Paralimni, Peyia, Pissouri, Polis, Protaras, etc.

Czech Republic: Bohemia, Brno, Děčín, Frymburk, Frýdek-Místek, Harrachov, Hradec Králové, Jihlava, Karlovy Vary, Kladno, Krkonoše, Kutná Hora, Liberec, Marienbad, Mikulov, Mladá Boleslav, Mělník, Olomouc, Ostrava, Pardubice, Plzeň, Poděbrady, Prague, Teplice, Třeboň, Zlín, Znojmo, Ústí nad Labem, České Budějovice, Český Krumlov, Špindlerův Mlýn, etc.

Democratic Republic of the Congo: Kinshasa, etc.

Denmark: Aalborg, Aarhus, Billund, Copenhagen, Ebeltoft, Esbjerg, Frederikshavn, Greenland, Helsingør, Herning, Hirtshals, Hjørring, Holstebro, Jutland, Odense, Silkeborg, Skagen, Skive, Sønderborg, Vejle, Viborg, etc.

Djibouti: Djibouti City, etc.

Dominican Republic: Boca Chica, Bávaro, Punta Cana, Santo Domingo, Sosúa, etc.

Ecuador: Baños, Cuenca, Galápagos Islands, Guayaquil, Manta, Otavalo, Puerto Ayora, Puerto López, Quito, Salinas, etc.

Egypt: Abu Simbel, Al Qusair, Alexandria, Aswan, Cairo, Dahab, El Alamein, El Gouna, El Hadaba, Faiyum, Giza, Hurghada, Luxor, Marsa Alam, Mersa Matruh, Naama Bay, Nabq Bay, Nile, Nuweiba, Port Said, Red Sea, Safaga, Sahl Hasheesh, Scharm asch-Schaich, Sharks Bay, Sinai, Suez, Taba, Valley of the Kings, etc.

El Salvador: La Libertad, San Salvador, etc.

Equatorial Guinea: Malabo, etc.

Eritrea: Asmara, etc.

Estonia: Haapsalu, Kuressaare, Narva, Pärnu, Saaremaa, Tallinn, Tartu, etc.

Ethiopia: Addis Ababa, Bahir Dar, Gondar, etc.

Faroe Islands: Tórshavn, etc.

Fiji: Nadi, Suva, Viti Levu Island, etc.

Finland: Espoo, Helsinki, Imatra, Joensuu, Jyväskylä, Jämsä, Kotka, Kuopio, Kuusamo, Lahti, Lapland, Lappeenranta, Levi, Mariehamn, Mikkeli, Moomin World, Naantali, Nilsiä, Oulu, Pori, Porvoo, Pyhätunturi, Rovaniemi, Rukatunturi, Saariselkä, Saimaa, Tampere, Turku, Vaasa, Vantaa, Vuokatti, Åland Islands, etc.

France: Aix-en-Provence, Ajaccio, Alsace, Annecy, Antibes, Aquitaine, Arles, Avignon, Avoriaz, Beaune, Biarritz, Bonifacio, Bordeaux, Briançon, Brittany, Burgundy, Cabourg, Cagnes-sur-Mer, Calais, Calvi, Canet-en-Roussillon, Cannes, Carcassonne, Cassis, Chambéry, Chamonix, Colmar, Corsica, Courchevel, Deauville, Dijon, Dunkirk, French Alps, French Riviera, Fréjus, Grenoble, Honfleur, La Ciotat, La Plagne, La Rochelle, Le Havre, Les Arcs, Les Gets, Les Menuires, Lille, Limoges, Lourdes, Lyon, Mandelieu-la-Napoule, Marseille, Megève, Menton, Montpellier, Morzine, Méribel, Nantes, Nice, Nord-Pas-de-Calais, Normandy, Paradiski, Paris, Pas-de-Calais, Portes du Soleil, Porto-Vecchio, Provence, Périgueux, Reims, Rhône-Alpes, Rouen, Saint-Gervais-les-Bains, Saint-Malo, Saint-Martin-de-Belleville, Saint-Rémy-de-Provence, Saint-Tropez, Saintes-Maries-de-la-Mer, Strasbourg, The Three Valleys, Tignes, Toulouse, Trouville-sur-Mer, Val Thorens, Val-d'Isère, Versailles, Île-de-France, etc.

French Guiana: Cayenne, Kourou, etc.

French Polynesia: Bora Bora, Mo'orea, Papeete, Tahiti, etc.

Gabon: Libreville, etc.

Gambia: Banjul, Serekunda, etc.

Georgia: Bakuriani, Batumi, Borjomi, Gudauri, Kobuleti, Kutaisi, Mestia, Sighnaghi, Stepantsminda, Tbilisi, Telavi, Zugdidi, etc.

Germany: Aachen, Augsburg, Bad Ems, Bad Füssing, Bad Harzburg, Bad Homburg, Bad Kissingen, Bad Neuenahr-Ahrweiler, Bad Reichenhall, Bad Salzuflen, Bad Schandau, Baden-Baden, Baden-Württemberg, Bamberg, Bavaria, Berchtesgaden, Berlin, Bernkastel-Kues, Bielefeld, Binz, Bonn, Brandenburg, Braunlage, Braunschweig, Bremen, Bremerhaven, Chemnitz, Cochem, Cologne, Cuxhaven, Dortmund, Dresden, Duisburg, Düsseldorf, Eisenach, Erfurt, Erlangen, Essen, Europa-Park, Frankfurt, Freiburg, Friedrichshafen, Fürth, Füssen, Garmisch-Partenkirchen, Goslar, Görlitz, Göttingen, Hamburg, Hanover, Heidelberg, Heiligendamm, Heligoland, Hesse, Ingolstadt, Inzell, Karlsruhe, Kiel, Koblenz, Lake Constance, Leipzig, Lindau, Lower Saxony, Lübeck, Magdeburg, Mainz, Mannheim, Marburg, Mecklenburg-Vorpommern, Munich, Münster, Neuschwanstein Castle, Neuss, Norddeich, Norden, North Rhine-Westphalia, Nuremberg, Oberstdorf, Oldenburg, Osnabrück, Paderborn, Potsdam, Quedlinburg, Regensburg, Rhineland-Palatinate, Rostock, Rothenburg ob der Tauber, Ruhpolding, Rust, Rügen, Saarbrücken, Saarland, Saxony, Saxony-Anhalt, Schleswig-Holstein, Schmallenberg, Schwerin, Schönau am Königsee, Sindelfingen, Speyer, Stuttgart, Sylt, Thuringia, Travemünde, Trier, Ulm, Warnemünde, Weimar, Wernigerode, Westerland, Wiesbaden, Wolfsburg, Würzburg, etc.

Ghana: Accra, Kumasi, etc.

Gibraltar:, etc.

Greece: Acharavi, Aegina, Afantou, Afytos, Agios Gordios, Andros, Arkadia, Athens, Cephalonia, Chania, Chaniotis, Chios, Corfu, Corinth, Crete, Cyclades, Dassia, Delphi, Dodecanese, Faliraki, Halkidiki, Heraklion, Hersonissos, Hydra, Ialysos, Ionian Islands, Kalamata, Kalavryta, Kalymnos, Kardamaina, Karpathos, Kassandra, Kastoria, Katerini, Kavos, Kefalos, Kokkari, Kos, Kriopigi, Laganas, Lefkada, Lemnos, Lesbos, Lindos, Loutraki, Marathokampos, Meteora, Mithymna, Monemvasia, Mount Athos, Mykonos, Mytilene, Nafplio, Naxos, Neos Marmaras, Paleokastritsa, Parga, Patmos, Patras, Pefkochori, Pefkos, Peloponnese, Polychrono, Poros, Pythagoreio, Rethymno, Rhodes, Samos, Samothrace, Santorini, Sidari, Sithonia, Sparta, Spetses, Sporades, Syros, Thasos, Thessaloniki, Tingaki, Zakynthos, etc.

Guadeloupe: Saint-François, etc.

Guam: Tamuning, Tumon, etc.

Guatemala: Antigua Guatemala, etc.

Guinea: Conakry, etc.

Guyana: Georgetown, etc.

Haiti: Cap-Haitien, Port-au-Prince, etc.

Honduras: Roatán, Tegucigalpa, etc.

Hong Kong: Causeway Bay, Hong Kong Island, Kowloon, Mong Kok, New Territories, Repulse Bay, Tsim Sha Tsui, Wan Chai, etc.

Hungary: Budapest, Eger, Gyula, Hajdúszoboszló, Hévíz, Lake Balaton, Pécs, Siófok, Szeged, Zalakaros, etc.

Iceland: Akureyri, Höfn, Kópavogur, Reykjavik, etc.

India: Agra, Ahmedabad, Allahabad, Aurangabad, Bangalore, Chennai, Darjeeling, Delhi, Gangtok, Goa, Gurgaon, Haridwar, Hyderabad, Jaipur, Jaisalmer, Karnataka, Kerala, Khajuraho, Kochi, Kolhapur, Kolkata, Ladakh, Leh, Madurai, Maharashtra, Manali, Mangalore, Mumbai, Nagpur, Nashik, New Delhi, Pune, Punjab, Rajasthan, Rishikesh, Sikkim, Srinagar, Thiruvananthapuram, Varanasi, Varkala, etc.

Indonesia: Bali, Balikpapan, Bandung, Batu, Bintan, Bogor, Borobudur, Denpasar, Jakarta, Java, Jimbaran, Kalimantan, Kuta, Lombok, Makassar, Malang, Mataram, Medan, Nusa Dua, Padang, Palembang, Pekanbaru, Sanur, Semarang, Seminyak, Sumatra, Surabaya, Surakarta, Ubud, Yogyakarta, etc.

Iran: Isfahan, Mashhad, Shiraz, Tehran, etc.

Iraq: Baghdad, Basra, Duhok, Erbil, Karbala, Sulaymaniyah, etc.

Ireland: Bundoran, Connemara, Cork, Dingle, Donegal, Doolin, Dublin, Ennis, Galway, Kenmare, Kilkenny, Killarney, Letterkenny, Limerick, Shannon, Tralee, Westport, etc.

Isle of Man: Douglas, etc.

Israel: Acre, Arad, Ashdod, Ashkelon, Bat Yam, Beersheba, Caesarea, Dead Sea, Eilat, Ein Bokek, Galilee, Golan Heights, Gush Dan, Haifa, Hermon, Herzliya, Jerusalem, Mitzpe Ramon, Nahariya, Nazareth, Netanya, Petah Tikva, Ramat Gan, Rosh Pinna, Safed, Tel Aviv, Tiberias, Zikhron Ya'akov, etc.

Italy: Abano Terme, Abruzzo, Agrigento, Alassio, Alberobello, Alghero, Amalfi Coast, Aosta Valley, Apulia, Arezzo, Arzachena, Assisi, Asti, Bardolino, Bari, Basilicata, Bellagio, Bellaria-Igea Marina, Benevento, Bergamo, Bologna, Bolzano, Bordighera, Bormio, Brescia, Breuil-Cervinia, Brindisi, Cagliari, Calabria, Campania, Canazei, Caorle, Capri, Carrara, Castiglione della Pescaia, Catania, Cefalù, Cervia, Cesenatico, Chioggia, Cinque Terre, Cortina d'Ampezzo, Cortona, Costa Smeralda, Courmayeur, Desenzano del Garda, Dolomites, Elba, Emilia-Romagna, Ercolano, Fasano, Fassa Valley, Ferrara, Finale Ligure, Florence, Forte dei Marmi, Gallipoli, Genoa, Golfo Aranci, Greve in Chianti, Grosseto, Gubbio, Herculaneum, Imperia, Ischia, Italian Alps, Jesolo, La Spezia, Lake Como, Lake Garda, Lake Maggiore, Lampedusa, Lazio, Lazise, Lecco, Lerici, Lido di Jesolo, Lignano Sabbiadoro, Liguria, Livigno, Livorno, Lombardy, Lucca, Madonna di Campiglio, Malcesine, Manarola, Mantua, Maratea, Massa, Matera, Menaggio, Merano, Messina, Mestre, Milan, Milazzo, Monopoli, Montecatini Terme, Montepulciano, Monterosso al Mare, Monza, Naples, Nardò, Novara, Olbia, Ortisei, Ostuni, Otranto, Padua, Palermo, Parma, Perugia, Pescara, Peschici, Peschiera del Garda, Piacenza, Piedmont, Pisa, Pistoia, Polignano a Mare, Pompeii, Porto Cervo, Porto Cesareo, Portoferraio, Portofino, Positano, Prato, Ragusa, Rapallo, Ravenna, Riccione, Rimini, Riomaggiore, Riva del Garda, Rome, Salerno, San Gimignano, Sanremo, Sardinia, Savona, Sestriere, Sicily, Siena, Siracusa, Sirmione, Sorrento, Sottomarina, Stresa, Sëlva, Taormina, Taranto, Trani, Trapani, Trentino-Alto Adige, Trento, Treviso, Trieste, Turin, Tuscany, Umbria, Urbino, Val Gardena, Veneto, Venice, Ventimiglia, Verbania, Vernazza, Verona, Vesuvius, Viareggio, Vicenza, Vieste, etc.

Ivory Coast: Abidjan, etc.

Jamaica: Kingston, Montego Bay, Negril, Ocho Rios, Port Antonio, Runaway Bay, etc.

Japan: Atami, Fujisawa, Fukuoka, Furano, Hakodate, Hakone, Hakuba, Hamamatsu, Hiroshima, Hokkaido, Ishigaki, Itō, Kagoshima, Kanagawa, Kanazawa, Karuizawa, Kawasaki, Kobe, Kutchan, Kyoto, Matsumoto, Miyakojima, Nagasaki, Nagoya, Naha, Nanjō, Nikkō, Okinawa, Onna, Osaka, Sapporo, Sendai, Shizuoka, Takayama, Tokyo, Yokohama, etc.

Jordan: Amman, Aqaba, Irbid, Jerash, Madaba, Petra, Sweimeh, Wadi Musa, Wadi Rum, Zarqa, etc.

Kazakhstan: Aktau, Aktobe, Almaty, Astana, Atyrau, Burabay, Karagandy, Kokshetau, Kostanay, Lake Balkhash, Oskemen, Pavlodar, Semey, Shymbulak, Shymkent, Taraz, etc.

Kenya: Kisumu, Lake Victoria, Masai Mara, Mombasa, Nairobi, Ukunda, etc.

Kongo: Brazzaville, Pointe-Noire, etc.

Kosovo: Pristina, Prizren, etc.

Kuwait: Hawally, Kuwait City, Salmiya, etc.

Kyrgyzstan: Bishkek, Bosteri, Cholpon-Ata, Issyk Kul, Karakol, Osh, etc.

Laos: Luang Prabang, Vientiane, etc.

Latvia: Cēsis, Daugavpils, Jūrmala, Liepāja, Riga, Rēzekne, Sigulda, Ventspils, etc.

Lebanon: Baalbeck, Beirut, Byblos, Faraya, Jounieh, Mzaar Kfardebian, Tripoli Lebanon, etc.

Lesotho: Maseru, etc.

Libya: Tripoli, etc.

Liechtenstein: Schaan, Vaduz, etc.

Lithuania: Druskininkai, Kaunas, Klaipėda, Nida, Palanga, Panevėžys, Trakai, Vilnius, Šiauliai, Šventoji, etc.

Luxembourg: Luxembourg City, etc.

Macau:, etc.

Macedonia: Bitola, Mavrovo, Ohrid, Skopje, etc.

Madagascar: Antananarivo, etc.

Malawi: Blantyre, Lilongwe, etc.

Malaysia: Borneo, George Town, Ipoh, Johor Bahru, Johor, Kedah, Kota Bharu, Kota Kinabalu, Kuah, Kuala Lumpur, Kuala Terengganu, Kuantan, Kuching, Langkawi, Malacca, Penang, Putrajaya, Sabah, Sarawak, Selangor, Shah Alam, etc.

Maldives: Kaafu Atoll, Malé, etc.

Mali: Bamako, etc.

Malta: Buġibba, Gozo, Mellieħa, Paceville, Qawra, Sliema, St. Julian's, Valletta, etc.

Martinique: Fort-de-France, Les Trois-Îlets, Sainte-Luce, etc.

Mauritania: Nouakchott, etc.

Mauritius: Port Louis, etc.

Mexico: Acapulco, Akumal, Cabo San Lucas, Cancún, Chetumal, Chichen Itza, Cozumel, Cuernavaca, Guadalajara, Guanajuato, Isla Mujeres, Los Cabos, Manzanillo, Mazatlán, Mexico City, Monterrey, Mérida, Oaxaca, Playa del Carmen, Puebla, Puerto Aventuras, Puerto Escondido, Puerto Morelos, Puerto Peñasco, Puerto Vallarta, Querétaro, Riviera Maya, San Cristóbal de las Casas, San Miguel de Allende, San Miguel de Cozumel, Tulum, etc.

Moldova: Bălți, Chișinău, Tiraspol, etc.

Monaco: Monte Carlo, etc.

Mongolia: Ulaanbaatar, etc.

Montenegro: Bar, Bečići, Bijela, Budva, Cetinje, Dobra Voda, Dobrota, Herceg Novi, Igalo, Kolašin, Kotor, Miločer, Nikšić, Perast, Petrovac, Podgorica, Prčanj, Sutomore, Sveti Stefan, Tivat, Ulcinj, Žabljak, etc.

Morocco: Agadir, Asilah, Casablanca, Chefchaouen, El Jadida, Essaouira, Fez, Marrakesh, Meknes, Merzouga, Mohammedia, Nador, Ouarzazate, Rabat, Tangier, Taroudant, Tinghir, Tétouan, etc.

Mozambique: Maputo, etc.

Myanmar: Mandalay, Yangon, etc.

Namibia: Windhoek, etc.

Nepal: Chitwan, Himalayas, Kathmandu, Lukla, Lumbini, Mount Everest, Nagarkot, Namche Bazaar, Patan, Pokhara, Tengboche, etc.

Netherlands: Amsterdam, Delft, Domburg, Eindhoven, Groningen, Haarlem, Leiden, Maastricht, Noordwijk, Rotterdam, Texel, The Hague, Utrecht, Zandvoort, etc.

New Zealand: Auckland, Christchurch, Dunedin, Queenstown, Rotorua, Wellington, etc.

Nicaragua: Granada, Managua, etc.

Nigeria: Abuja, Benin City, Calabar, Enugu, Ibadan, Ilorin, Jos, Kaduna, Lagos, Owerri, Port Harcourt, Uyo, etc.

North Korea: Pyongyang, etc.

Northern Mariana Islands: Saipan, etc.

Norway: Beitostølen, Bergen, Bodø, Gardermoen, Geilo, Geirangerfjord, Hardangerfjord, Hemsedal, Kristiansand, Larvik, Lillehammer, Lofoten, Narvik, Oslo, Sognefjord, Stavanger, Stryn, Svalbard, Tromsø, Trondheim, Ålesund, etc.

Oman: Muscat, Nizwa, Salalah, Seeb, etc.

Pakistan: Bhurban, Faisalabad, Islamabad, Karachi, Lahore, Peshawar, Rawalpindi, etc.

Palau: Koror, Peleliu, etc.

Palestine: Beit Sahour, Bethlehem, Hebron, Jericho, Nablus, Ramallah, etc.

Panama: Bocas del Toro, Panama City, etc.

Papua New Guinea: Port Moresby, etc.

Paraguay: Asunción, Ciudad Del Este, Encarnación, etc.

Peru: Arequipa, Ayacucho, Cajamarca, Chiclayo, Cusco, Huancayo, Huanchaco, Huaraz, Ica, Iquitos, Lima, Machu Picchu, Máncora, Nazca, Ollantaytambo, Paracas, Pisco, Piura, Puerto Maldonado, Puno, Tacna, Tarapoto, Trujillo, Urubamba, etc.

Philippines: Angeles City, Bacolod, Baguio, Bohol, Boracay, Cagayan de Oro, Cebu, Davao, Dumaguete, El Nido, Kalibo, Lapu-Lapu City, Luzon, Mactan, Makati, Manila, Mindanao, Palawan, Panglao, Parañaque, Pasay, Pasig, Puerto Galera, Puerto Princesa, Quezon City, etc.

Poland: Białowieża Forest, Białystok, Bielsko-Biała, Bydgoszcz, Gdańsk, Gdynia, Katowice, Kielce, Kołobrzeg, Kraków, Lublin, Olsztyn, Oświęcim, Poznań, Rzeszów, Sopot, Szczecin, Toruń, Tricity, Warsaw, Wrocław, Zakopane, Zielona Góra, Łódź, Świnoujście, etc.

Portugal: Albufeira, Algarve, Azores, Funchal, Lagos, Lisbon, Madeira, Porto, Sintra, etc.

Puerto Rico: San Juan, etc.

Qatar: Doha, etc.

Romania: Bran, Brașov, Bucharest, Cluj-Napoca, Constanța, Poiana Brașov, Sibiu, Sighișoara, Timișoara, Transylvania, etc.

Russia: Abakan, Abrau-Dyurso, Abzakovo, Adler, Altai Republic, Alupka, Alushta, Anadyr, Anapa, Angarsk, Arkhangelsk, Arkhipo Osipovka, Armavir, Astrakhan, Bakhchysarai, Balakovo, Balashikha, Baltic Sea, Barnaul, Belgorod, Belokurikha, Biysk, Black Sea, Blagoveshchensk, Bolshoy Utrish, Bratsk, Bryansk, Caucasian Mineral Waters, Cheboksary, Chelyabinsk, Cherepovets, Cherkessk, Chita, Chornomorske, Crimea, Curonian Spit, Dagomys, Divnomorskoye, Dombay, Domodedovo, Dzerzhinsk, Dzhankhot, Dzhubga, Elektrostal, Elista, Engels, Estosadok, Feodosia, Foros, Gaspra, Gatchina, Gelendzhik, Golden Ring, Golubitskaya, Gornaya Karusel, Gorno-Altaysk, Goryachy Klyuch, Grozny, Gurzuf, Irkutsk, Ivanovo, Izhevsk, Kabardinka, Kaliningrad, Kaluga, Kamchatka, Karelia, Kazan, Kemerovo, Kerch, Khabarovsk, Khanty-Mansiysk, Khibiny, Khimki, Khosta, Kirov, Kirovsk, Kislovodsk, Kizhi, Koktebel, Kolomna, Komsomolsk on Amur, Konakovo, Koreiz, Korolev, Kostroma, Krasnaya Polyana, Krasnodar Krai, Krasnodar, Krasnogorsk, Krasnoyarsk, Kurgan, Kursk, Kyzyl, Lake Baikal, Lake Seliger, Lazarevskoye, Lipetsk, Listvyanka, Loo, Lyubertsy, Magadan, Magnitogorsk, Makhachkala, Massandra, Matsesta, Maykop, Miass, Mineralnye Vody, Moscow, Mount Elbrus, Murmansk, Murom, Mytishchi, Naberezhnye Chelny, Nakhodka, Nalchik, Naryan-Mar, Nebug, Nizhnekamsk, Nizhnevartovsk, Nizhny Novgorod, Nizhny Tagil, Norilsk, Novokuznetsk, Novorossiysk, Novosibirsk, Novyi Svit, Novyy Urengoy, Obninsk, Odintsovo, Olginka, Omsk, Orenburg, Orsk, Oryol, Partenit, Penza, Pereslavl Zalessky, Perm, Petergof, Petropavlovsk-Kamchatsky, Petrozavodsk, Plyos, Podolsk, Popovka, Primorsko-Akhtarsk, Pskov, Pulkovo, Pushkin, Pushkino, Pyatigorsk, Repino, Rosa Khutor, Rostov-on-Don, Ryazan, Rybachye, Rybinsk, Saint Petersburg, Sakhalin, Saky, Salekhard, Samara, Saransk, Saratov, Sea of Azov, Sergiyev Posad, Serpukhov, Sestroretsk, Sevastopol, Shakhty, Sheregesh, Sheremetyevo, Siberia, Simeiz, Simferopol, Smolensk, Sochi, Solovetsky Islands, Sortavala, Stary Oskol, Stavropol, Sterlitamak, Sudak, Sukko, Surgut, Suzdal, Svetlogorsk, Syktyvkar, Syzran, Taganrog, Tambov, Tarusa, Terskol, Tobolsk, Tolyatti, Tomsk, Torzhok, Tuapse, Tula, Tver, Tyumen, Ufa, Uglich, Ulan-Ude, Ulyanovsk, Utes, Valaam, Valday, Velikiye Luki, Veliky Novgorod, Veliky Ustyug, Vityazevo, Vladikavkaz, Vladimir, Vladivostok, Vnukovo International Airport, Volga, Volgograd, Vologda, Volzhskiy, Voronezh, Vyborg, Yakhroma, Yakutsk, Yalta, Yaroslavl, Yekaterinburg, Yelets, Yenisei, Yessentuki, Yevpatoria, Yeysk, Yoshkar-Ola, Yuzhno Sakhalinsk, Zelenogradsk, Zheleznovodsk, Zhukovsky, Zvenigorod, etc.

Rwanda: Butare, Gisenyi, Kibuye, Kigali, etc.

Réunion: Saint-Denis, etc.

Saint Barthélemy: Gustavia, etc.

Saint Kitts and Nevis: Basseterre, etc.

Saint Lucia: Anse La Raye, Castries, Gros Islet, Soufrière, etc.

Saint Martin:, etc.

Saint Vincent and the Grenadines: Kingstown, etc.

Samoa: Apia, etc.

San Marino: City of San Marino, etc.

Saudi Arabia: Al Khobar, Jeddah, Mecca, Medina, Riyadh, etc.

Senegal: Dakar, etc.

Serbia: Belgrade, Kopaonik, Niš, Novi Sad, Palić, Stara Planina, Subotica, Zlatibor, etc.

Seychelles: La Digue, Mahé, Praslin, etc.

Sierra Leone: Freetown, etc.

Singapore: Changi, Sentosa, etc.

Sint Maarten:, etc.

Slovakia: Bratislava, Jasná, Liptov, Tatranská Lomnica, Vysoké Tatry, Štrbské Pleso, etc.

Slovenia: Bled, Bohinj, Bovec, Kranjska Gora, Ljubljana, Maribor, Piran, Portorož, Rogaška Slatina, etc.

Solomon Islands: Honiara, etc.

South Africa: Cape Town, Durban, Johannesburg, Kruger National Park, Marloth Park, Port Elizabeth, Pretoria, etc.

South Korea: Busan, Daegu, Gyeongju, Incheon, Jejudo, Pyeongchang, Seogwipo, Seoul, Suwon, etc.

Spain: A Coruña, Alcúdia, Algeciras, Alicante, Almería, Altea, Andalusia, Antequera, Aragon, Asturias, Ayamonte, Balearic Islands, Barbate, Barcelona, Basque Country, Benalmádena, Benidorm, Benissa, Besalú, Bilbao, Blanes, Buñol, Cadaqués, Cala d'Or, Calella, Calonge, Calp, Calvià, Cambrils, Canary Islands, Cangas de Onís, Cantabria, Cartagena, Castilla-La Mancha, Catalonia, Chiclana de la Frontera, Costa Blanca, Costa Brava, Costa Dorada, Costa del Maresme, Costa del Sol, Cádiz, Córdoba, Dénia, El Puerto de Santa María, Empuriabrava, Estepona, Figueres, Formentera, Fuerteventura, Galicia, Gijón, Girona, Gran Canaria, Granada, Ibiza, Jerez de la Frontera, L'Escala, L'Estartit, L'Hospitalet de Llobregat, La Pineda, Lanzarote, Llançà, Lloret de Mar, Madrid, Magaluf, Malgrat de Mar, Mallorca, Marbella, Maspalomas, Menorca, Mijas, Mojácar, Moraira, Murcia, Málaga, Navarre, Nerja, Oviedo, Palma Nova, Palma, Pals, Pollença, PortAventura, Ronda, Roquetas de Mar, Roses, Salamanca, Salou, San Sebastian, Sant Antoni de Portmany, Santander, Santiago de Compostela, Santillana del Mar, Seville, Sidges, Sierra Nevada, Tarifa, Tarragona, Tenerife, Toledo, Torremolinos, Torrevieja, Torroella de Montgrí, Tossa de Mar, Valencia, Vélez-Málaga, Xàbia, Zaragoza, etc.

Sri Lanka: Anuradhapura, Bentota, Beruwala, Colombo, Dambulla, Galle, Hikkaduwa, Jaffna, Kandy, Mirissa, Negombo, Nuwara Eliya, Sigiriya, Tangalle, Trincomalee, Unawatuna, Weligama, etc.

Sudan: Khartoum, etc.

Suriname: Paramaribo, etc.

Swaziland: Lobamba, Mbabane, etc.

Sweden: Bohuslän, Gothenburg, Gotland, Helsingborg, Lund, Malmö, Stockholm, Uppsala, Visby, Åre, etc.

Switzerland: Adelboden, Andermatt, Anzère, Arosa, Ascona, Basel, Bellinzona, Bern, Crans-Montana, Davos, Engelberg, Fribourg, Geneva, Grindelwald, Gstaad, Haute-Nendaz, Interlaken, Jungfrau, Lake Maggiore, Lausanne, Lauterbrunnen, Locarno, Lucerne, Lugano, Matterhorn, Montreux, Nendaz, Neuchâtel, Pontresina, Portes du Soleil, Saas-Fee, Silvaplana, Sion, St. Gallen, St. Moritz, Swiss Alps, Ticino, Valais, Verbier, Vevey, Veysonnaz, Wengen, Zermatt, Zug, Zürich, etc.

Syria: Aleppo, Damascus, Latakia, Palmyra, etc.

Taiwan: Hsinchu, Kaohsiung, Taichung, Tainan, Taipei, etc.

Tajikistan: Dushanbe, Khujand, etc.

Tanzania: Dar es Salaam, Mount Kilimanjaro, Serengeti, Zanzibar, etc.

Thailand: Ayutthaya, Bangkok, Chiang Mai, Chiang Rai, Chonburi, Hua Hin, Kanchanaburi, Karon, Ko Chang, Ko Lanta, Ko Phangan, Ko Samui, Krabi, Pai, Patong, Pattaya, Phi Phi Islands, Phuket, Ranong, River Kwai, Udon Thani, etc.

Togo: Lomé, etc.

Tonga: Nukuʻalofa, etc.

Trinidad and Tobago: Port of Spain, etc.

Tunisia: Djerba, Hammamet, Midoun, Monastir, Port El Kantaoui, Sousse, Tunis, etc.

Turkey: Adana, Alacati, Alanya, Ankara, Antakya, Antalya, Ayvalık, Beldibi, Belek, Bodrum, Bozcaada, Bursa, Büyükada, Cappadocia, Dalyan, Datça, Denizli, Didim, Edirne, Ephesus, Erzurum, Eskişehir, Fethiye, Gaziantep, Göynük, Istanbul, Kalkan, Kayseri, Kaş, Kemer, Konakli, Konya, Kuşadası, Lara, Mahmutlar, Marmaris, Mersin, Olympos, Palandöken, Pamukkale, Prince Islands, Samsun, Sapanca, Sarıkamış, Selçuk, Side, Tekirova, Trabzon, Troy, Turkish Riviera, Uludağ, Van, Çamyuva, Çanakkale, Çeşme, Çıralı, Ölüdeniz, İzmir, İçmeler, Şanlıurfa, etc.

Turkmenistan: Ashgabat, Avaza, etc.

Turks and Caicos Islands: Cockburn Town, North Caicos, Pine Cay, Providenciales, etc.

U.S. Virgin Islands: Charlotte Amalie, etc.

Uganda: Kampala, etc.

Ukraine: Berdiansk, Bukovel, Chernivtsi, Dnipropetrovsk, Donetsk, Ivano-Frankivsk, Kamianets-Podilskyi, Kharkiv, Kherson, Kiev, Koblevo, Kremenchuk, Kryvyi Rih, Luhansk, Lviv, Mariupol, Mykolaiv, Odessa, Poltava, Slavske, Sumy, Truskavets, Uzhgorod, Vinnytsia, Yaremche, Zaporizhia, Zatoka, Zhytomyr, etc.

United Arab Emirates: Abu Dhabi, Ajman, Dubai, Persian Gulf, Ras Al Khaimah, Sharjah, etc.

United Kingdom: Aberdeen, Bath, Belfast, Blackpool, Bournemouth, Brighton, Bristol, Cambridge, Canterbury, Cardiff, Channel Tunnel, Cheltenham, Chester, Cornwall, Coventry, Cumbria, Derry, Devon, Dorset, Dover, Eastbourne, Edinburgh, England, English Channel, Exeter, Folkestone, Fort William, Glasgow, Hampshire, Inverness, Kent, Lancashire, Leeds, Leicester, Liverpool, Llandudno, London, Manchester, Milton Keynes, Newcastle, Newquay, Northern Ireland, Norwich, Nottingham, Oban, Oxford, Paignton, Plymouth, Portmeirion, Reading, Scarborough, Scotland, Sheffield, Somerset, Southampton, St Albans, Stonehenge, Sussex, Swansea, Torquay, Wales, Windsor, York, etc.

United States: Alabama, Alaska, Albuquerque, Amarillo, Anaheim, Anchorage, Arizona, Arkansas, Arlington, Aspen, Atlanta, Austin, Bakersfield, Baltimore, Beaver Creek, Billings, Birmingham, Boise, Boston, Breckenridge, Brooklyn, California, Carlsbad, Charlotte, Cheyenne, Chicago, Cincinnati, Clearwater, Cleveland, Colorado Springs, Colorado, Columbus, Connecticut, Corpus Christi, Dallas, Daytona Beach, Death Valley, Delaware, Denver, Des Moines, Destin, Detroit, El Paso, Estes Park, Fargo, Florida, Fort Lauderdale, Fort Myers, Fort Walton Beach, Fort Worth, Fresno, Galveston, Georgia, Grand Canyon, Grand Teton, Great Smoky Mountains, Hawaii, Hollywood, Honolulu, Hot Springs, Houston, Idaho, Illinois, Indiana, Indianapolis, Iowa, Irving, Jackson, Jackson, Jacksonville, Jersey City, Juneau, Kansas City, Kansas, Kentucky, Key Largo, Key West, Lahaina, Lake Tahoe, Las Vegas, Lexington, Little Rock, Long Beach, Los Angeles, Louisiana, Louisville, Madison, Maine, Manhattan, Marathon, Maryland, Massachusetts, Memphis, Miami Beach, Miami, Michigan, Milwaukee, Minneapolis, Minnesota, Mississippi, Missouri, Moab, Montana, Monterey, Mountain View, Myrtle Beach, Napa, Naples, Nashville, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New Orleans, New York City, New York, Newport, North Carolina, North Dakota, Oakland, Ocean City, Ohio, Oklahoma City, Oklahoma, Omaha, Oregon, Orlando, Palm Coast, Palm Desert, Palm Springs, Panama City Beach, Park City, Pasadena, Pennsylvania, Pensacola, Philadelphia, Phoenix, Pittsburgh, Plano, Portland, Portland, Providence, Raleigh, Reno, Rhode Island, Richmond, Rocky Mountains, Sacramento, Saint Paul, Salt Lake City, San Antonio, San Diego, San Francisco, Sanibel, Santa Barbara, Santa Cruz, Santa Fe, Santa Monica, Sarasota, Savannah, Scottsdale, Seattle, Silicon Valley, South Carolina, South Dakota, Springfield, Squaw Valley, St. Augustine, Steamboat Springs, Sunny Isles Beach, Tallahassee, Tampa, Telluride, Tennessee, Texas, Tucson, Tulsa, Utah, Vail, Vermont, Virginia Beach, Virginia, Waikiki, Washington D.C., Washington, West Virginia, Wichita, Wisconsin, Wyoming, Yellowstone, Yosemite, Zion, etc.

Uruguay: Montevideo, Punta del Este, etc.

Uzbekistan: Bukhara, Khiva, Samarkand, Tashkent, etc.

Vanuatu: Port Vila, etc.

Vatican City:, etc.

Venezuela: Caracas, Isla Margarita, Maracaibo, Porlamar, etc.

Vietnam: Cần Thơ, Da Lat, Da Nang, Haiphong, Hanoi, Ho Chi Minh City, Huế, Hạ Long, Hội An, Nha Trang, Phan Thiết, Phú Quốc, Sa Pa, Vũng Tàu, etc.

Yemen: Aden, Sana'a, etc.

Zambia: Livingstone, Lusaka, etc.

Zimbabwe: Bulawayo, Harare, Mutare, Victoria Falls, etc.

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